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The Masters of Arts program in AMCS is intended for students who wish to go into professional careers in Applied Mathematics, or wish to obtain sufficient background in Applied Mathematics to be a strong candidate for a doctoral program in Applied Mathematics, Mathematics, Statistics, and Financial Mathematics etc. While an undergraduate degree in Mathematics, or Applied Mathematics is not required, applicants to the program should have taken sufficiently many advanced undergraduate mathematics courses so that their interest in and aptitude for mathematics can be assessed. Beyond Calculus, two semesters of Mathematical Analysis, a semester of Linear Algebra, a semester of Probability, and a semester of Complex Analysis are strongly recommended. The master’s degree is typically earned in 3 to 4 semesters, depending upon the student's background.

Students in the masters program take at least eight graduate courses from the list of approved courses numbered 500 and above, including at least one each in applied algebra, applied analysis, probability and statistics, and numerical methods. With permission of the Graduate Group Chair, certain courses with a 400-number may be counted toward the course requirement for the Masters degree. The other courses can be in pure mathematics, applied mathematics, and courses offered by other departments, which make essential usage of advanced mathematics. Every student's program of study must be approved by the graduate group chair. There is also a requirement to pass the Written Preliminary Exam and to submit and defend a Master’s thesis, or take two additional courses in lieu of the Master’s thesis, with the approval of the Graduate Group Chair. To receive the Masters degree a student must have at least a 3.0 cumulative grade point average in courses counted toward the degree.

Course requirements: A minimum of eight units of graduate courses at the University of Pennsylvania, numbered 500 and above (or, rarely, 400-level courses with the permission of the Chair), is required for the Masters degree. Other than MATH 546-7, most 500 level Mathematics courses are not accepted. This list of courses must usually include courses in applied algebra, applied analysis, probability and statistics, and numerical methods. The list of courses must be approved by the Graduate Group Chair of the AMCS graduate group. To be approved there must be a preponderance of graduate-level mathematics courses. To receive the Masters degree a student must have at least a 3.0 cumulative grade point average in courses counted toward the degree.